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Image Search Results
Journal: Chinese Medicine
Article Title: Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa
doi: 10.1186/s13020-021-00481-8
Figure Lengend Snippet: In vitro screening of 13 plant extracts with antibiofilm activities against clinical resistant isolates of PA. a The distribution of MIC values against levofloxacin of 96 clinical isolates of PA. b The level of biofilm formation in 12 resistant strains of PA. c The MIC values of 13 plant extracts against PA1803 and ATCC 27853. d The antibiofilm activities of 13 plant extracts against PA1803 at MIC and 1/2MIC. *P < 0.05, compared with corresponding control
Article Snippet: Fig. 1 In vitro screening of 13 plant extracts with antibiofilm activities against clinical resistant isolates of PA. a The distribution of
Techniques: In Vitro, Control
Journal: Chinese Medicine
Article Title: Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa
doi: 10.1186/s13020-021-00481-8
Figure Lengend Snippet: Active antibiofilm compounds from metabolites of CA in LJF. a Antibiofilm activity of LJF and CA. b Growth curves of bacterial growth at different sub-MICs of CA. c GC–MS analysis of CA at 0.5, 1, 2, 4, 6, 24 h. The red arrow indicates the location of the peak of CA. d Measured ion spectrum (upper) and matched ion spectrum in NIST17 database (lower) of CA. e Metabolic pathways of CA in intestine (left) and liver (right). f In vitro antibiofilm effects of CA and its intestinal metabolites. g In vitro antibiofilm effects of CA and its liver metabolites. h GC–MS analysis of quinic acid at 0.5, 1, 2, 4, 6, 24 h. The red arrow indicates the location of the peak of quinic acid. i Measured ion spectrum (upper) and matched ion spectrum in NIST17 database (lower) of quinic acid. j The antibacterial activity ratio of caffeic acid and quinic acid to CA. k The antibacterial activity ratio of caffeic acid and its main metabolites to CA. l , m The antibacterial activity ratio of quinic acid and its major metabolites to CA. n – o Effects of dihydrocaffeic acid and gallic acid on the integrity (n) and the permeability (o) of bacteria membrane against MRSA. p - q Effects of dihydrocaffeic acid on the integrity ( p ) and the permeability ( q ) of bacteria membrane against MSSA. r Effects of quinic acid on EPS secretion in biofilm formation (upper) and in mature biofilm (lower). s – u The synergistic antibiofilm effects of sub-MIC quinic acid with levofloxacin ( s ), clarithromycin ( t ) and azithromycin ( v ). QA: quinic acid. *P < 0.05, **P < 0.01, compared with corresponding control
Article Snippet: Fig. 1 In vitro screening of 13 plant extracts with antibiofilm activities against clinical resistant isolates of PA. a The distribution of
Techniques: Activity Assay, Gas Chromatography-Mass Spectrometry, In Vitro, Permeability, Bacteria, Membrane, Control